Nuclear Magnetic Resonance (NMR)
Overview
Nuclear Magnetic Resonance (NMR) is a highly versatile technique employed in both biological and chemical analyses for the precise determination of molecular identity and structure. This technique harnesses the power of magnetic fields and electromagnetic frequencies to investigate the nuclei of samples, recording radio frequencies emitted during the process.
When subjected to a magnetic field, nuclei within the sample exhibit unique magnetic properties. The interaction of these nuclei with the magnetic field results in distinct precessions, a phenomenon known as chemical shifts. These chemical shifts offer invaluable insights into the structural composition of molecules.
In H-NMR (Proton Nuclear Magnetic Resonance), each hydrogen nucleus is meticulously measured, yielding multiple peaks and distinctive chemical shift patterns. Variants of NMR include Carbon NMR (C-NMR), Solid-State NMR (SS-NMR), Fluorine NMR, and Sulfur NMR, all operating on similar principles to unravel the mysteries of molecular structure.
Services
- H-NMR
- C-NMR
- F-NMR
- Si-NMR
- Solid State NMR
Pricing
- Regular service: Starts from $150 per sample with 4 – 5 days turnaround.
- For a comprehensive overview of our pricing structure, please log in to the Bee Portal.
Equipment
- Bruker Avance III HD 800
- Bruker Avance III HD 700
- Bruker Avance III HD 500
- Bruker Avance III 400
- Bruker AV III H/d 300
FAQ
A: NMR analysis, short for Nuclear Magnetic Resonance analysis, is a powerful analytical technique that investigates the nuclear properties of atoms within a sample. It works by exposing the sample to a strong magnetic field and radiofrequency pulses, causing atomic nuclei to align with the magnetic field. When the nuclei return to their equilibrium states, they emit characteristic radiofrequency signals that can be used to determine the sample’s composition and structure.
A: NMR analysis can provide a wide range of information, such as identification of chemical compounds, molecular structure elucidation, quantification of specific nuclei, dynamics and interactions within molecules.
A: NMR analysis has diverse applications across various fields, including:
- Chemistry: Identifying and characterizing organic and inorganic compounds.
- Pharmaceutical Sciences: Studying drug formulations and interactions.
- Biology: Investigating protein structures and biomolecular interactions.
- Material Science: Analyzing polymers, catalysts, and materials.
A: NMR analysis can be applied to a wide range of samples, including liquids, solids, and gases. It is particularly valuable for studying complex organic molecules, proteins, and other biological samples.
A: Yes, NMR analysis is versatile and can be used for both qualitative and quantitative purposes. When NMR is used quantitatively it is called qNMR and can identify substances and provide quantitative data, such as concentrations and molar ratios.
A: NMR is technically non-destructive. Your sample is dissolved into a deuterated solvent and can be roto-vaporized to recover the sample.
A: Only a small amount of sample is needed for analysis 5-10 mgs is typically enough.
A: NMR analysis offers several advantages:
- High structural resolution.
- Detailed information on molecular dynamics.
- Non-destructive analysis.
- Versatility in sample types.
- Minimal sample preparation.
A: At Outermost Technology, we offer NMR analysis services to meet your analytical needs. Our expertise and state-of-the-art equipment enable precise measurements and in-depth analysis for a wide range of applications.